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Dynamics Description

The Adaptive Recovery process reflects an asymmetric regulatory dynamic between two latent constructsβ€”such as stress and copingβ€”where activation in one system initiates a corrective response in the other. Specifically, stress tends to increase coping responses, while coping reduces subsequent stress, producing a negative feedback loop that promotes stability and recovery.

Individuals differ in the strength and balance of these cross-regulatory influences, leading to variability in how quickly they return to equilibrium after disturbances. The process noise covariance is moderate and negatively correlated, representing compensatory fluctuations where increases in stress are often accompanied by decreases in coping, while measurement error variance is small and symmetric across variables.

This configuration captures a psychologically meaningful stress-response mechanism, characterized by self-correcting dynamics that stabilize the system over time through coordinated but asymmetric influences.

Model

The measurement model is given by 𝐲i,t=πš²π›ˆi,t+𝛆i,t,with𝛆i,tβˆΌπ’©(𝟎,𝚯)\begin{equation} \mathbf{y}_{i, t} = \boldsymbol{\Lambda} \boldsymbol{\eta}_{i, t} + \boldsymbol{\varepsilon}_{i, t}, \quad \mathrm{with} \quad \boldsymbol{\varepsilon}_{i, t} \sim \mathcal{N} \left( \mathbf{0}, \boldsymbol{\Theta} \right) \end{equation} where 𝐲i,t\mathbf{y}_{i, t}, π›ˆi,t\boldsymbol{\eta}_{i, t}, and 𝛆i,t\boldsymbol{\varepsilon}_{i, t} are random variables and 𝚲\boldsymbol{\Lambda}, and 𝚯\boldsymbol{\Theta} are model parameters. 𝐲i,t\mathbf{y}_{i, t} represents a vector of observed random variables, π›ˆi,t\boldsymbol{\eta}_{i, t} a vector of latent random variables, and 𝛆i,t\boldsymbol{\varepsilon}_{i, t} a vector of random measurement errors, at time tt and individual ii. 𝚲\boldsymbol{\Lambda} denotes a matrix of factor loadings, and 𝚯\boldsymbol{\Theta} the covariance matrix of 𝛆\boldsymbol{\varepsilon} that is invariant across individuals. In this model, 𝚲\boldsymbol{\Lambda} is an identity matrix and 𝚯\boldsymbol{\Theta} is a symmetric matrix.

The dynamic structure is given by π›ˆi,t=𝛂i+𝛃iπ›ˆi,tβˆ’1+𝛇i,t,with𝛇i,tβˆΌπ’©(𝟎,𝚿)\begin{equation} \boldsymbol{\eta}_{i, t} = \boldsymbol{\alpha}_{i} + \boldsymbol{\beta}_{i} \boldsymbol{\eta}_{i, t - 1} + \boldsymbol{\zeta}_{i, t}, \quad \mathrm{with} \quad \boldsymbol{\zeta}_{i, t} \sim \mathcal{N} \left( \mathbf{0}, \boldsymbol{\Psi} \right) \end{equation} where π›ˆi,t\boldsymbol{\eta}_{i, t}, π›ˆi,tβˆ’1\boldsymbol{\eta}_{i, t - 1}, and 𝛇i,t\boldsymbol{\zeta}_{i, t} are random variables, and 𝛃i\boldsymbol{\beta}_{i}, and 𝚿\boldsymbol{\Psi} are model parameters. Here, π›ˆi,t\boldsymbol{\eta}_{i, t} is a vector of latent variables at time tt and individual ii, π›ˆi,tβˆ’1\boldsymbol{\eta}_{i, t - 1} represents a vector of latent variables at time tβˆ’1t - 1 and individual ii, and 𝛇i,t\boldsymbol{\zeta}_{i, t} represents a vector of dynamic noise at time tt and individual ii. 𝛃i\boldsymbol{\beta}_{i} is a matrix of autoregression and cross regression coefficients for individual ii, and 𝚿\boldsymbol{\Psi} the covariance matrix of 𝛇i,t\boldsymbol{\zeta}_{i, t} that is invariant across all individuals. In this model, 𝚿\boldsymbol{\Psi} is a symmetric matrix.

Alternative Parameterization

An alternative parameterization of the dynamic structure that directly estimates the set-point vector 𝛍i\boldsymbol{\mu}_{i} is given by π›ˆi,t=𝛍i+𝛃i(π›ˆi,tβˆ’1βˆ’π›i)+𝛇i,t.\begin{equation} \boldsymbol{\eta}_{i, t} = \boldsymbol{\mu}_{i} + \boldsymbol{\beta}_{i} \left( \boldsymbol{\eta}_{i, t - 1} - \boldsymbol{\mu}_{i} \right) + \boldsymbol{\zeta}_{i, t} . \end{equation}

Algebraic manipulation of the equation results in the following π›ˆi,t=𝛍iβˆ’π›ƒi𝛍i+𝛃iπ›ˆi,tβˆ’1+𝛇i,t,\begin{equation} \boldsymbol{\eta}_{i, t} = \boldsymbol{\mu}_{i} - \boldsymbol{\beta}_{i} \boldsymbol{\mu}_{i} + \boldsymbol{\beta}_{i} \boldsymbol{\eta}_{i, t - 1} + \boldsymbol{\zeta}_{i, t} , \end{equation} where we can see that the intercept vector 𝛂i\boldsymbol{\alpha}_{i} is implied by 𝛍iβˆ’π›ƒi𝛍i\boldsymbol{\mu}_{i} - \boldsymbol{\beta}_{i} \boldsymbol{\mu}_{i}.

Data Generation

Notation

Let t=1000t = 1000 be the number of time points and n=1000n = 1000 be the number of individuals. We simulate a total of time =11000= 11000 points per individual, discarding the first 1000010000 as burn-in. The analysis uses the final 10001000 measurement occasions.

Let the factor loadings matrix 𝚲\boldsymbol{\Lambda} be given by 𝚲=(1001).\begin{equation} \boldsymbol{\Lambda} = \left( \begin{array}{cc} 1 & 0 \\ 0 & 1 \\ \end{array} \right) . \end{equation}

Let the measurement error covariance matrix 𝚯\boldsymbol{\Theta} be given by 𝚯=(0.5000.5).\begin{equation} \boldsymbol{\Theta} = \left( \begin{array}{cc} 0.5 & 0 \\ 0 & 0.5 \\ \end{array} \right) . \end{equation}

Let the initial condition π›ˆ0\boldsymbol{\eta}_{0} be given by π›ˆ0βˆΌπ’©(π›π›ˆβˆ£0,πšΊπ›ˆβˆ£0).\begin{equation} \boldsymbol{\eta}_{0} \sim \mathcal{N} \left( \boldsymbol{\mu}_{\boldsymbol{\eta} \mid 0}, \boldsymbol{\Sigma}_{\boldsymbol{\eta} \mid 0} \right) . \end{equation}π›π›ˆβˆ£0\boldsymbol{\mu}_{\boldsymbol{\eta} \mid 0} and πšΊπ›ˆβˆ£0\boldsymbol{\Sigma}_{\boldsymbol{\eta} \mid 0} are functions of 𝛂\boldsymbol{\alpha} and 𝛃\boldsymbol{\beta}.

Let the intercept vector 𝛂\boldsymbol{\alpha} be normally distributed with the following means (0.80.5)\begin{equation} \left( \begin{array}{c} 0.8 \\ 0.5 \\ \end{array} \right) \end{equation} and covariance matrix (0.150.050.050.1).\begin{equation} \left( \begin{array}{cc} 0.15 & 0.05 \\ 0.05 & 0.1 \\ \end{array} \right) . \end{equation}

Let the transition matrix 𝛃\boldsymbol{\beta} be normally distributed with the following means (0.6βˆ’0.30.250.7)\begin{equation} \left( \begin{array}{cc} 0.6 & -0.3 \\ 0.25 & 0.7 \\ \end{array} \right) \end{equation} and covariance matrix (0.0250.01000.010.0200000.020.01000.010.025).\begin{equation} \left( \begin{array}{cccc} 0.025 & 0.01 & 0 & 0 \\ 0.01 & 0.02 & 0 & 0 \\ 0 & 0 & 0.02 & 0.01 \\ 0 & 0 & 0.01 & 0.025 \\ \end{array} \right) . \end{equation}

The SimAlphaN and SimBetaN functions from the simStateSpace package generate random intercept vectors and transition matrices from the multivariate normal distribution. Note that the SimBetaN function generates transition matrices that are weakly stationary with an option to set lower and upper bounds. The person-specific set-point vector 𝛍i\boldsymbol{\mu}_{i} was derived from the generated 𝛂i\boldsymbol{\alpha}_{i} and 𝛃i\boldsymbol{\beta}_{i}.

Let the dynamic process noise 𝚿\boldsymbol{\Psi} be given by 𝚿=(0.25βˆ’0.1βˆ’0.10.22).\begin{equation} \boldsymbol{\Psi} = \left( \begin{array}{cc} 0.25 & -0.1 \\ -0.1 & 0.22 \\ \end{array} \right) . \end{equation}

R Function Arguments

n
#> [1] 1000
time
#> [1] 11000
burnin
#> [1] 10000
# first mu0 in the list of length n
mu0[[1]]
#> [1] -0.6409103  1.8437611
# first sigma0 in the list of length n
sigma0[[1]]
#>            [,1]       [,2]
#> [1,]  0.6803744 -0.2369735
#> [2,] -0.2369735  0.3548975
# first sigma0_l in the list of length n
sigma0_l[[1]] # sigma0_l <- t(chol(sigma0))
#>            [,1]      [,2]
#> [1,]  0.8248481 0.0000000
#> [2,] -0.2872935 0.5218811
# first alpha in the list of length n
alpha[[1]]
#> [1] 0.5941503 0.6684587
# first beta in the list of length n
beta[[1]]
#>           [,1]       [,2]
#> [1,] 0.5736830 -0.4704412
#> [2,] 0.1415191  0.6866418
# first psi in the list of length n
psi[[1]]
#>       [,1]  [,2]
#> [1,]  0.25 -0.10
#> [2,] -0.10  0.22
psi_l[[1]] # psi_l <- t(chol(psi))
#>      [,1]      [,2]
#> [1,]  0.5 0.0000000
#> [2,] -0.2 0.4242641
nu
#> [[1]]
#> [1] 0 0
lambda
#> [[1]]
#>      [,1] [,2]
#> [1,]    1    0
#> [2,]    0    1
theta
#> [[1]]
#>      [,1] [,2]
#> [1,]  0.5  0.0
#> [2,]  0.0  0.5
theta_l # theta_l <- t(chol(theta))
#> [[1]]
#>           [,1]      [,2]
#> [1,] 0.7071068 0.0000000
#> [2,] 0.0000000 0.7071068
# first mu_eta (set-point) in the list of length n
mu_eta[[1]]
#> [1] -0.6409103  1.8437611

Visualizing the Dynamics Without Process Noise and Measurement Error (n = 5 with Different Initial Condition)

Using the SimSSMIVary Function from the simStateSpace Package to Simulate Data

library(simStateSpace)
sim <- SimSSMIVary(
  n = n,
  time = time,
  mu0 = mu0,
  sigma0_l = sigma0_l,
  alpha = alpha,
  beta = beta,
  psi_l = psi_l,
  nu = nu,
  lambda = lambda,
  theta_l = theta_l
)
data <- as.data.frame(sim, burnin = burnin)
head(data)
#>   id time         y1        y2
#> 1  1    0 -1.3784256 3.4783987
#> 2  1    1 -1.7787675 2.2002487
#> 3  1    2  0.1032886 1.2379348
#> 4  1    3 -0.2237299 0.8511623
#> 5  1    4 -1.1157617 2.0194513
#> 6  1    5 -0.1886396 1.5396721
plot(sim, burnin = burnin)

Model Fitting

The FitDTVARMxID function fits a DT-VAR model on each individual ii. To set up the estimation, we first provide starting values for each parameter matrix.

Set-Point (mu_eta)

The set-point vector 𝛍\boldsymbol{\mu} is initialized with starting values.

mu_eta_values <- mu_eta

Autoregressive Parameters (beta)

We initialize the autoregressive coefficient matrix 𝛃\boldsymbol{\beta} with the true values used in simulation.

beta_values <- beta

LDL’-parameterized covariance matrices

Covariances such as psi and theta are estimated using the LDL’ decomposition of a positive definite covariance matrix. The decomposition expresses a covariance matrix Ξ£\Sigma as
𝚺=(𝐋+𝐈)diag(Softplus(𝐝uc))(𝐋+𝐈)β€²,\begin{equation} \boldsymbol{\Sigma} = \left( \mathbf{L} + \mathbf{I} \right) \mathrm{diag} \left( \mathrm{Softplus} \left( \mathbf{d}_{uc} \right) \right) \left( \mathbf{L} + \mathbf{I} \right)^{\prime}, \end{equation} where: - 𝐋\mathbf{L} is a strictly lower-triangular matrix of free parameters (l_mat_strict),
- 𝐈\mathbf{I} is the identity matrix,
- 𝐝uc\mathbf{d}_{uc} is an unconstrained vector,
- Softplus(𝐝uc)=log⁑(1+exp(𝐝uc))\mathrm{Softplus} \left(\mathbf{d}_{uc} \right) = \log \left(1 + \exp \left( \mathbf{d}_{uc} \right) \right) ensures strictly positive diagonal entries.

The LDL() function extracts this decomposition from a positive definite covariance matrix. It returns:
- d_uc: unconstrained diagonal parameters, equal to InvSoftplus(d_vec),
- d_vec: diagonal entries, equal to Softplus(d_uc),
- l_mat_strict: the strictly lower-triangular factor.

sigma <- matrix(
  data = c(1.0, 0.5, 0.5, 1.0),
  nrow = 2,
  ncol = 2
)
ldl_sigma <- LDL(sigma)
d_uc <- ldl_sigma$d_uc
l_mat_strict <- ldl_sigma$l_mat_strict
I <- diag(2)
sigma_reconstructed <- (l_mat_strict + I) %*% diag(log1p(exp(d_uc)), 2) %*% t(l_mat_strict + I)
sigma_reconstructed
#>      [,1] [,2]
#> [1,]  1.0  0.5
#> [2,]  0.5  1.0

Process Noise Covariance Matrix (psi)

Starting values for the process noise covariance matrix 𝚿\boldsymbol{\Psi} are given below, with corresponding LDL’ parameters.

psi_values <- psi[[1]]
ldl_psi_values <- LDL(psi_values)
psi_d_values <- ldl_psi_values$d_uc
psi_l_values <- ldl_psi_values$l_mat_strict
psi_d_values
#> [1] -1.258692 -1.623449
psi_l_values
#>      [,1] [,2]
#> [1,]  0.0    0
#> [2,] -0.4    0

Measurement Error Covariance Matrix (theta)

Starting values for the measurement error covariance matrix 𝚯\boldsymbol{\Theta} are given below, with corresponding LDL’ parameters.

theta_values <- theta[[1]]
ldl_theta_values <- LDL(theta_values)
theta_d_values <- ldl_theta_values$d_uc
theta_l_values <- ldl_theta_values$l_mat_strict
theta_d_values
#> [1] -0.4327521 -0.4327521
theta_l_values
#>      [,1] [,2]
#> [1,]    0    0
#> [2,]    0    0

Initial mean vector (mu_0) and covariance matrix (sigma_0)

The initial mean vector π›πŸŽ\boldsymbol{\mu_0} and covariance matrix 𝚺𝟎\boldsymbol{\Sigma_0} are fixed using mu0 and sigma0.

mu0_values <- mu0
sigma0_values <- lapply(
  X = sigma0,
  FUN = LDL
)
sigma0_d_values <- lapply(
  X = sigma0_values,
  FUN = function(i) {
    i$d_uc
  }
)
sigma0_l_values <- lapply(
  X = sigma0_values,
  FUN = function(i) {
    i$l_mat_strict
  }
)

FitDTVARMxID

fit <- FitDTVARMxID(
  data = data,
  observed = c("y1", "y2"),
  id = "id",
  center = TRUE,
  mu_eta_values = mu_eta_values,
  beta_values = beta_values,
  psi_d_values = psi_d_values,
  psi_l_values = psi_l_values,
  theta_d_values = theta_d_values,
  mu0_values = mu0_values,
  sigma0_d_values = sigma0_d_values,
  sigma0_l_values = sigma0_l_values,
  ncores = parallel::detectCores()
)

Parameter estimates

head(summary(fit))
#>                             beta_1_1   beta_2_1   beta_1_2  beta_2_2 mu_eta_1_1
#> FitDTVARMxID_DTVAR_ID1.Rds 0.4354550 0.17318034 -0.8617860 0.7654212 -0.5891073
#> FitDTVARMxID_DTVAR_ID2.Rds 0.3723701 0.60873921 -0.3355289 0.9928778  0.1821793
#> FitDTVARMxID_DTVAR_ID3.Rds 0.5090962 0.43699533 -0.1897852 0.8883645  0.3937449
#> FitDTVARMxID_DTVAR_ID4.Rds 0.6211980 0.17807858 -0.1433649 0.5820667  1.0160762
#> FitDTVARMxID_DTVAR_ID5.Rds 0.6419239 0.22464598 -0.2416318 0.7745309 -0.8752583
#> FitDTVARMxID_DTVAR_ID6.Rds 0.4912871 0.02894239 -0.2063216 0.6044975  0.9047161
#>                            mu_eta_2_1  psi_l_2_1 psi_d_1_1 psi_d_2_1
#> FitDTVARMxID_DTVAR_ID1.Rds   1.785867 -0.3603330 -1.838030 -1.802444
#> FitDTVARMxID_DTVAR_ID2.Rds   6.061074 -0.4465356 -1.254230 -2.289462
#> FitDTVARMxID_DTVAR_ID3.Rds   4.190544 -0.3889435 -1.583936 -1.441315
#> FitDTVARMxID_DTVAR_ID4.Rds   4.097153 -0.6286424 -1.208268 -1.613658
#> FitDTVARMxID_DTVAR_ID5.Rds   3.992908 -0.4504113 -1.163153 -1.758080
#> FitDTVARMxID_DTVAR_ID6.Rds   2.626440 -0.1484303 -1.025647 -1.244879
#>                            theta_d_1_1 theta_d_2_1
#> FitDTVARMxID_DTVAR_ID1.Rds  -0.4881215  -0.2447964
#> FitDTVARMxID_DTVAR_ID2.Rds  -0.3589143  -0.2971942
#> FitDTVARMxID_DTVAR_ID3.Rds  -0.3636831  -0.5559566
#> FitDTVARMxID_DTVAR_ID4.Rds  -0.2978613  -0.4055079
#> FitDTVARMxID_DTVAR_ID5.Rds  -0.4315600  -0.5602322
#> FitDTVARMxID_DTVAR_ID6.Rds  -0.7717579  -0.4389711

Proportion of converged cases

converged(
  fit,
  theta_tol = 0.01,
  prop = TRUE
)
#> [1] 0.975

Fixed-Effect Meta-Analysis of Measurement Error

When fitting DT-VAR models per person, separating process noise (𝚿\boldsymbol{\Psi}) from measurement error (𝚯\boldsymbol{\Theta}) can be unstable for some individuals. To stabilize inference, we first pool the person-level 𝚯i\boldsymbol{\Theta}_{i} estimates from only the converged fits using a fixed-effect meta-analysis. This yields a high-precision estimate of the common measurement-error covariance that we will then hold fixed in a second pass of model fitting.

What the code does: - Selects individuals that converged and whose 𝚯i\boldsymbol{\Theta}_i diagonals exceed a small threshold (theta_tol), filtering out near-zero or ill-conditioned solutions. - Extracts each person’s LDL’ diagonal parameters for 𝚯i\boldsymbol{\Theta}_i and their sampling covariance matrices. - Computes the inverse-variance-weighted pooled estimate (fixed effect), returning it on the same LDL’ parameterization used by FitDTVARMxID().

library(metaVAR)
fixed_theta <- MetaVARMx(
  fit,
  random = FALSE, # TRUE by default
  effects = FALSE, # TRUE by default
  cov_meas = TRUE, # FALSE by default
  theta_tol = 0.01,
  ncores = parallel::detectCores()
)

You can read summary(fixed_theta) as providing the pooled (fixed) measurement-error scale that is common across persons. If individual instruments truly share the same reliability structure, fixing 𝚯\boldsymbol{\Theta} to this pooled value improves stability and often reduces bias in the dynamic parameters.

Note: Fixed-effect pooling assumes a common 𝚯\boldsymbol{\Theta} across individuals.

coef(fixed_theta)
#>  alpha_1_1  alpha_2_1 
#> -0.3932456 -0.4085644
summary(fixed_theta)
#> [1] 0
#> Call:
#> MetaVARMx(object = fit, random = FALSE, effects = FALSE, cov_meas = TRUE, 
#>     theta_tol = 0.01, ncores = parallel::detectCores())
#> 
#> CI type = "normal"
#>                est     se        z p    2.5%   97.5%
#> alpha[1,1] -0.3932 0.0041 -94.8567 0 -0.4014 -0.3851
#> alpha[2,1] -0.4086 0.0041 -98.5010 0 -0.4167 -0.4004
theta_d_values <- coef(fixed_theta)

Refit the model with fixed measurement error covariance matrix

We refit the individual models using the pooled 𝚯\boldsymbol{\Theta} as a fixed measurement-error covariance matrix.

fit <- FitDTVARMxID(
  data = data,
  observed = c("y1", "y2"),
  id = "id",
  center = TRUE,
  mu_eta_values = mu_eta_values,
  beta_values = beta_values,
  psi_d_values = psi_d_values,
  psi_l_values = psi_l_values,
  theta_fixed = TRUE,
  theta_d_values = theta_d_values,
  mu0_values = mu0_values,
  sigma0_d_values = sigma0_d_values,
  sigma0_l_values = sigma0_l_values,
  ncores = parallel::detectCores()
)

With 𝚯\boldsymbol{\Theta} fixed, the re-estimation focuses on the dynamic structure (𝛍\boldsymbol{\mu}, 𝛃\boldsymbol{\beta}, 𝚿\boldsymbol{\Psi}). In practice, this often increases the proportion of converged fits and yields more stable cross-lag estimates.

Proportion of converged cases

converged(
  fit,
  prop = TRUE
)
#> [1] 1

Random-Effects Meta-Analysis of Person-Specific Dynamics and Means

Having stabilized 𝚯\boldsymbol{\Theta}, we synthesize the person-specific estimates to recover population-level effects and their between-person variability. We use a random-effects model so the pooled mean reflects both within-person estimation uncertainty and between-person heterogeneity.

random <- MetaVARMx(
  fit,
  effects = TRUE,
  set_point = TRUE,
  robust_v = FALSE,
  robust = TRUE,
  ncores = parallel::detectCores()
)
summary(random)
#> [1] 0
#> Call:
#> MetaVARMx(object = fit, effects = TRUE, set_point = TRUE, robust_v = FALSE, 
#>     robust = TRUE, ncores = parallel::detectCores())
#> 
#> CI type = "normal"
#>                  est     se           z      p    2.5%   97.5%
#> alpha[1,1]    0.4551 0.0369     12.3290 0.0000  0.3827  0.5274
#> alpha[2,1]    2.5637 0.0768     33.4014 0.0000  2.4133  2.7142
#> alpha[3,1]    0.6104 0.0048    126.7204 0.0000  0.6010  0.6198
#> alpha[4,1]    0.2560 0.0045     56.9874 0.0000  0.2472  0.2648
#> alpha[5,1]   -0.2933 0.0047    -62.7708 0.0000 -0.3024 -0.2841
#> alpha[6,1]    0.7055 0.0047    150.5207 0.0000  0.6964  0.7147
#> tau_sqr[1,1]  1.3597 0.0611     22.2544 0.0000  1.2400  1.4795
#> tau_sqr[2,1] -0.5171 0.0913     -5.6638 0.0000 -0.6960 -0.3382
#> tau_sqr[3,1]  0.0232 0.0056      4.1445 0.0000  0.0122  0.0341
#> tau_sqr[4,1]  0.0005 0.0052      0.1026 0.9183 -0.0096  0.0106
#> tau_sqr[5,1]  0.0367 0.0054      6.7934 0.0000  0.0261  0.0473
#> tau_sqr[6,1] -0.0574 0.0056    -10.2249 0.0000 -0.0684 -0.0464
#> tau_sqr[2,2]  5.8883 0.2643     22.2771 0.0000  5.3702  6.4063
#> tau_sqr[3,2]  0.0193 0.0116      1.6656 0.0958 -0.0034  0.0421
#> tau_sqr[4,2]  0.0323 0.0109      2.9698 0.0030  0.0110  0.0536
#> tau_sqr[5,2]  0.1253 0.0114     10.9545 0.0000  0.1029  0.1477
#> tau_sqr[6,2]  0.1689 0.0121     13.9952 0.0000  0.1452  0.1925
#> tau_sqr[3,3]  0.0203 0.0010     19.4258 0.0000  0.0182  0.0223
#> tau_sqr[4,3]  0.0070 0.0007      9.7506 0.0000  0.0056  0.0084
#> tau_sqr[5,3] -0.0012 0.0007     -1.6789 0.0932 -0.0025  0.0002
#> tau_sqr[6,3] -0.0012 0.0007     -1.7696 0.0768 -0.0026  0.0001
#> tau_sqr[4,4]  0.0176 0.0009     19.4539 0.0000  0.0158  0.0193
#> tau_sqr[5,4] -0.0012 0.0006     -1.8426 0.0654 -0.0025  0.0001
#> tau_sqr[6,4] -0.0016 0.0006     -2.4664 0.0136 -0.0029 -0.0003
#> tau_sqr[5,5]  0.0179 0.0009     18.9322 0.0000  0.0160  0.0197
#> tau_sqr[6,5]  0.0075 0.0007     10.5852 0.0000  0.0061  0.0089
#> tau_sqr[6,6]  0.0184 0.0010     19.1763 0.0000  0.0165  0.0203
#> i_sqr[1,1]    0.9987 0.0001  17355.3529 0.0000  0.9986  0.9988
#> i_sqr[2,1]    0.9998 0.0000 101397.0457 0.0000  0.9998  0.9998
#> i_sqr[3,1]    0.9463 0.0026    361.5838 0.0000  0.9411  0.9514
#> i_sqr[4,1]    0.9553 0.0022    443.4095 0.0000  0.9510  0.9595
#> i_sqr[5,1]    0.9486 0.0024    389.0382 0.0000  0.9439  0.9534
#> i_sqr[6,1]    0.9650 0.0017    582.2637 0.0000  0.9617  0.9682

Normal Theory Confidence Intervals

confint(random, level = 0.95, lb = FALSE)
#>                     2.5 %        97.5 %
#> alpha[1,1]    0.382739785  5.274317e-01
#> alpha[2,1]    2.413288001  2.714162e+00
#> alpha[3,1]    0.600964249  6.198463e-01
#> alpha[4,1]    0.247216344  2.648270e-01
#> alpha[5,1]   -0.302427411 -2.841132e-01
#> alpha[6,1]    0.696359343  7.147335e-01
#> tau_sqr[1,1]  1.239993658  1.479502e+00
#> tau_sqr[2,1] -0.696024774 -3.381504e-01
#> tau_sqr[3,1]  0.012203814  3.410266e-02
#> tau_sqr[4,1] -0.009583580  1.064267e-02
#> tau_sqr[5,1]  0.026120352  4.730393e-02
#> tau_sqr[6,1] -0.068402668 -4.639715e-02
#> tau_sqr[2,2]  5.370212295  6.406328e+00
#> tau_sqr[3,2] -0.003419562  4.211302e-02
#> tau_sqr[4,2]  0.010979585  5.360109e-02
#> tau_sqr[5,2]  0.102885064  1.477234e-01
#> tau_sqr[6,2]  0.145239954  1.925453e-01
#> tau_sqr[3,3]  0.018225741  2.231622e-02
#> tau_sqr[4,3]  0.005588043  8.399720e-03
#> tau_sqr[5,3] -0.002530219  1.954092e-04
#> tau_sqr[6,3] -0.002600107  1.327059e-04
#> tau_sqr[4,4]  0.015782911  1.931945e-02
#> tau_sqr[5,4] -0.002468608  7.620572e-05
#> tau_sqr[6,4] -0.002876701 -3.291126e-04
#> tau_sqr[5,5]  0.016036043  1.973975e-02
#> tau_sqr[6,5]  0.006117691  8.898010e-03
#> tau_sqr[6,6]  0.016527841  2.029101e-02
#> i_sqr[1,1]    0.998604912  9.988305e-01
#> i_sqr[2,1]    0.999760965  9.997996e-01
#> i_sqr[3,1]    0.941141587  9.514001e-01
#> i_sqr[4,1]    0.951039346  9.594843e-01
#> i_sqr[5,1]    0.943869824  9.534284e-01
#> i_sqr[6,1]    0.961739516  9.682360e-01
confint(random, level = 0.99, lb = FALSE)
#>                     0.5 %        99.5 %
#> alpha[1,1]    0.360007044  5.501644e-01
#> alpha[2,1]    2.366017199  2.761433e+00
#> alpha[3,1]    0.597997660  6.228129e-01
#> alpha[4,1]    0.244449508  2.675938e-01
#> alpha[5,1]   -0.305304783 -2.812358e-01
#> alpha[6,1]    0.693472553  7.176203e-01
#> tau_sqr[1,1]  1.202364105  1.517132e+00
#> tau_sqr[2,1] -0.752250918 -2.819242e-01
#> tau_sqr[3,1]  0.008763255  3.754322e-02
#> tau_sqr[4,1] -0.012761354  1.382044e-02
#> tau_sqr[5,1]  0.022792171  5.063211e-02
#> tau_sqr[6,1] -0.071859985 -4.293984e-02
#> tau_sqr[2,2]  5.207426779  6.569113e+00
#> tau_sqr[3,2] -0.010573249  4.926670e-02
#> tau_sqr[4,2]  0.004283261  6.029741e-02
#> tau_sqr[5,2]  0.095840455  1.547680e-01
#> tau_sqr[6,2]  0.137807742  1.999775e-01
#> tau_sqr[3,3]  0.017583081  2.295888e-02
#> tau_sqr[4,3]  0.005146296  8.841467e-03
#> tau_sqr[5,3] -0.002958446  6.236364e-04
#> tau_sqr[6,3] -0.003029463  5.620619e-04
#> tau_sqr[4,4]  0.015227280  1.987508e-02
#> tau_sqr[5,4] -0.002868427  4.760249e-04
#> tau_sqr[6,4] -0.003276956  7.114253e-05
#> tau_sqr[5,5]  0.015454149  2.032164e-02
#> tau_sqr[6,5]  0.005680871  9.334829e-03
#> tau_sqr[6,6]  0.015936605  2.088224e-02
#> i_sqr[1,1]    0.998569472  9.988659e-01
#> i_sqr[2,1]    0.999754892  9.998057e-01
#> i_sqr[3,1]    0.939529857  9.530118e-01
#> i_sqr[4,1]    0.949712553  9.608111e-01
#> i_sqr[5,1]    0.942368069  9.549301e-01
#> i_sqr[6,1]    0.960718840  9.692567e-01

Robust Confidence Intervals

confint(random, level = 0.95, lb = FALSE, robust = TRUE)
#>                     2.5 %        97.5 %
#> alpha[1,1]    0.382569928  5.276015e-01
#> alpha[2,1]    2.412705804  2.714745e+00
#> alpha[3,1]    0.600976455  6.198341e-01
#> alpha[4,1]    0.247172965  2.648704e-01
#> alpha[5,1]   -0.302728782 -2.838118e-01
#> alpha[6,1]    0.696076904  7.150159e-01
#> tau_sqr[1,1]  1.043429463  1.676067e+00
#> tau_sqr[2,1] -1.004187692 -2.998745e-02
#> tau_sqr[3,1]  0.010631414  3.567506e-02
#> tau_sqr[4,1] -0.010097914  1.115700e-02
#> tau_sqr[5,1]  0.025873522  4.755076e-02
#> tau_sqr[6,1] -0.071712154 -4.308767e-02
#> tau_sqr[2,2]  4.135404398  7.641136e+00
#> tau_sqr[3,2] -0.001947614  4.064107e-02
#> tau_sqr[4,2]  0.011882391  5.269828e-02
#> tau_sqr[5,2]  0.099505921  1.511025e-01
#> tau_sqr[6,2]  0.136967417  2.008179e-01
#> tau_sqr[3,3]  0.018258977  2.228298e-02
#> tau_sqr[4,3]  0.005592482  8.395281e-03
#> tau_sqr[5,3] -0.002481984  1.471749e-04
#> tau_sqr[6,3] -0.002522937  5.553628e-05
#> tau_sqr[4,4]  0.015822486  1.927988e-02
#> tau_sqr[5,4] -0.002457828  6.542526e-05
#> tau_sqr[6,4] -0.002784668 -4.211454e-04
#> tau_sqr[5,5]  0.016066790  1.970900e-02
#> tau_sqr[6,5]  0.006111479  8.904222e-03
#> tau_sqr[6,6]  0.016452707  2.036614e-02
#> i_sqr[1,1]    0.998419785  9.990156e-01
#> i_sqr[2,1]    0.999714050  9.998465e-01
#> i_sqr[3,1]    0.941225199  9.513165e-01
#> i_sqr[4,1]    0.951078915  9.594447e-01
#> i_sqr[5,1]    0.943868351  9.534298e-01
#> i_sqr[6,1]    0.961735979  9.682396e-01
confint(random, level = 0.99, lb = FALSE, robust = TRUE)
#>                     0.5 %        99.5 %
#> alpha[1,1]    0.359783814  5.503876e-01
#> alpha[2,1]    2.365252063  2.762198e+00
#> alpha[3,1]    0.598013701  6.227969e-01
#> alpha[4,1]    0.244392499  2.676509e-01
#> alpha[5,1]   -0.305700852 -2.808398e-01
#> alpha[6,1]    0.693101365  7.179915e-01
#> tau_sqr[1,1]  0.944034964  1.775461e+00
#> tau_sqr[2,1] -1.157245642  1.230705e-01
#> tau_sqr[3,1]  0.006696771  3.960971e-02
#> tau_sqr[4,1] -0.013437303  1.449639e-02
#> tau_sqr[5,1]  0.022467782  5.095650e-02
#> tau_sqr[6,1] -0.076209386 -3.859044e-02
#> tau_sqr[2,2]  3.584614119  8.191926e+00
#> tau_sqr[3,2] -0.008638781  4.733224e-02
#> tau_sqr[4,2]  0.005469750  5.911092e-02
#> tau_sqr[5,2]  0.091399508  1.592089e-01
#> tau_sqr[6,2]  0.126935786  2.108495e-01
#> tau_sqr[3,3]  0.017626760  2.291520e-02
#> tau_sqr[4,3]  0.005152131  8.835632e-03
#> tau_sqr[5,3] -0.002895055  5.602457e-04
#> tau_sqr[6,3] -0.002928045  4.606438e-04
#> tau_sqr[4,4]  0.015279291  1.982307e-02
#> tau_sqr[5,4] -0.002854259  4.618570e-04
#> tau_sqr[6,4] -0.003156004 -4.980906e-05
#> tau_sqr[5,5]  0.015494557  2.028123e-02
#> tau_sqr[6,5]  0.005672707  9.342993e-03
#> tau_sqr[6,6]  0.015837861  2.098099e-02
#> i_sqr[1,1]    0.998326174  9.991092e-01
#> i_sqr[2,1]    0.999693236  9.998673e-01
#> i_sqr[3,1]    0.939639742  9.529019e-01
#> i_sqr[4,1]    0.949764555  9.607591e-01
#> i_sqr[5,1]    0.942366133  9.549321e-01
#> i_sqr[6,1]    0.960714192  9.692614e-01

Profile-Likelihood Confidence Intervals

confint(random, level = 0.95, lb = TRUE)
#> Error in `[.data.frame`:
#> ! undefined columns selected
confint(random, level = 0.99, lb = TRUE)
#> Error in `[.data.frame`:
#> ! undefined columns selected
  • The fixed part of the random-effects model gives pooled means 𝛂=𝔼[Vec(𝛍,𝛃)]\boldsymbol{\alpha} = \mathbb{E} \left[ \mathrm{Vec} \left( \boldsymbol{\mu}, \boldsymbol{\beta} \right) \right].
  • The random part yields between-person covariances (𝛕2\boldsymbol{\tau}^{2}) quantifying heterogeneity in set-point (𝛍\boldsymbol{\mu}) and dynamics (𝛃\boldsymbol{\beta}) across individuals.
means <- extract(random, what = "alpha")
means
#> [1]  0.4550857  2.5637252  0.6104053  0.2560217 -0.2932703  0.7055464
covariances <- extract(random, what = "tau_sqr")
covariances
#>               [,1]        [,2]         [,3]          [,4]         [,5]
#> [1,]  1.3597480348 -0.51708757  0.023153239  0.0005295449  0.036712139
#> [2,] -0.5170875722  5.88826996  0.019346727  0.0322903374  0.125304219
#> [3,]  0.0231532390  0.01934673  0.020270978  0.0069938814 -0.001167405
#> [4,]  0.0005295449  0.03229034  0.006993881  0.0175511823 -0.001196201
#> [5,]  0.0367121386  0.12530422 -0.001167405 -0.0011962012  0.017887896
#> [6,] -0.0573999114  0.16889264 -0.001233700 -0.0016029067  0.007507850
#>              [,6]
#> [1,] -0.057399911
#> [2,]  0.168892639
#> [3,] -0.001233700
#> [4,] -0.001602907
#> [5,]  0.007507850
#> [6,]  0.018409425

Finally, we compare the meta-analytic population estimates to the known generating values.

pop_mean
#> [1]  0.4408869  2.6095167  0.5990229  0.2511529 -0.3048517  0.6895688
pop_cov
#>              [,1]        [,2]          [,3]         [,4]          [,5]
#> [1,]  1.406089868 -0.53172453  2.334149e-02 1.792627e-03  3.819205e-02
#> [2,] -0.531724531  7.32735340  3.345138e-02 3.769325e-02  1.504922e-01
#> [3,]  0.023341485  0.03345138  2.380050e-02 9.249947e-03 -4.466312e-05
#> [4,]  0.001792627  0.03769325  9.249947e-03 1.909528e-02  2.736111e-04
#> [5,]  0.038192047  0.15049219 -4.466312e-05 2.736111e-04  1.885667e-02
#> [6,] -0.061114643  0.19748361 -5.601484e-04 1.248519e-05  8.802218e-03
#>               [,6]
#> [1,] -6.111464e-02
#> [2,]  1.974836e-01
#> [3,] -5.601484e-04
#> [4,]  1.248519e-05
#> [5,]  8.802218e-03
#> [6,]  2.238834e-02

Summary

This vignette demonstrates a two-stage hierarchical estimation approach for dynamic systems: 1. individual-level DT-VAR estimation with stabilized measurement error, and
2. population-level meta-analysis of person-specific dynamics and means.

References

Hunter, M. D. (2017). State space modeling in an open source, modular, structural equation modeling environment. Structural Equation Modeling: A Multidisciplinary Journal, 25(2), 307–324. https://doi.org/10.1080/10705511.2017.1369354
Neale, M. C., Hunter, M. D., Pritikin, J. N., Zahery, M., Brick, T. R., Kirkpatrick, R. M., Estabrook, R., Bates, T. C., Maes, H. H., & Boker, S. M. (2015). OpenMx 2.0: Extended structural equation and statistical modeling. Psychometrika, 81(2), 535–549. https://doi.org/10.1007/s11336-014-9435-8
R Core Team. (2024). R: A language and environment for statistical computing. R Foundation for Statistical Computing. https://www.R-project.org/